Florence

Florence Rosebell K. Nankya, MBChB Study coordinator MIND Study, Research Assistant COHRE grant proposal, Part-time coordinator UO1 study, Study doctor HBMF study, Medical Doctor – Kitagata Hospital, Volunteer Medical officer Gynecology emergency Ward Mulago Hospital, Regional Trainer-of-trainers Life saving skills MOH Mulago and a Registered Midwife. Affiliation: MU-UCSF Research Collaboration E-mail Address: fnankya@gmail.com
Professional Interests: Public Health, Clinical and operational Research activities; Clinical care in obstetrics and gynecology; Management of Tuberculosis in adults and children; and Malaria management and Treatment. Current Main Activities: I am currently working as a Study coordinator for the Kampala City branch of the study described below as well as undertaking my studies for a Masters in Public Health as an external student. International HIV-associated Opportunistic Pneumonias (IHOP) Study. This is an NIH-funded prospective study of HIV-associated pneumonia conducted in 3 cites representing the current HIV/AIDS epidemic in Africa (Kampala, Uganda), Europe (London, United Kingdom), and USA (San Francisco, CA) and involving 6 independent laboratories at the NIH, the University of California San Francisco, the University of Cincinnati, and the University of North Carolina. The goals of this study are: (1) To determine the frequency and mortality of HIV-associated opportunistic pneumonias in an international, multi-center, longitudinal cohort and to test the hypothesis that PCP is associated with increased mortality. (2) To estimate the sensitivity and specificity of molecular tools for PCP and TB diagnosis and to test the hypotheses that 60-second oropharyngeal washing (OPW, gargle) specimens combined with polymerase chain reaction (PCR) assays are sensitive tests to diagnose PCP and TB. (3) To test the hypothesis that P. jirovecii dihydropteroate synthase (DHPS) gene mutations are associated with an increased morbidity and mortality and to explore potential mechanisms, and (4) To characterize the predominant P. jirovecii Msg-C variant recognized by antibodies at the 3 study sites, to examine systemic (serum) and local (BAL) antibody responses, and to test the hypotheses that the level of antibodies to the predominant variant is correlated with PCP status. The IHOP Study serves as the foundation for complementary research studies, led by MU-UCSF Investigators William Worodria, MBChB, MMed, J. Lucian (Luke) Davis, MD, and Adithya Cattamanchi, MD. Education and Training: Masters in Public Health (Distance Learning course) 2007 Sept. – ongoing Makerere University MBChB Degree 1998-2003 Life saving skills training 96 Feb-Sept 1996 Certified Trainer of Trainers in Safe motherhood obstetric care. Mulago School of Nursing Registered Midwife 1991-1994

Florence Rosebell K. Nankya, MBChB

Study coordinator MIND Study,
Research Assistant COHRE grant proposal,
Part-time coordinator UO1 study, Study doctor HBMF study,
Medical Doctor – Kitagata Hospital,
Volunteer Medical officer Gynecology emergency Ward Mulago Hospital,
Regional Trainer-of-trainers Life saving skills MOH Mulago and a Registered Midwife.

Affiliation: MU-UCSF Research Collaboration

E-mail Address: fnankya@gmail.com

Professional Interests:
Public Health, Clinical and operational Research activities; Clinical care in obstetrics and gynecology; Management of Tuberculosis in adults and children; and Malaria management and Treatment.

Current Main Activities:
I am currently working as a Study coordinator for the Kampala City branch of the study described below as well as undertaking my studies for a Masters in Public Health as an external student.

International HIV-associated Opportunistic Pneumonias (IHOP) Study. This is an NIH-funded prospective study of HIV-associated pneumonia conducted in 3 cites representing the current HIV/AIDS epidemic in Africa (Kampala, Uganda), Europe (London, United Kingdom), and USA (San Francisco, CA) and involving 6 independent laboratories at the NIH, the University of California San Francisco, the University of Cincinnati, and the University of North Carolina. The goals of this study are: (1) To determine the frequency and mortality of HIV-associated opportunistic pneumonias in an international, multi-center, longitudinal cohort and to test the hypothesis that PCP is associated with increased mortality. (2) To estimate the sensitivity and specificity of molecular tools for PCP and TB diagnosis and to test the hypotheses that 60-second oropharyngeal washing (OPW, gargle) specimens combined with polymerase chain reaction (PCR) assays are sensitive tests to diagnose PCP and TB. (3) To test the hypothesis that P. jirovecii dihydropteroate synthase (DHPS) gene mutations are associated with an increased morbidity and mortality and to explore potential mechanisms, and (4) To characterize the predominant P. jirovecii Msg-C variant recognized by antibodies at the 3 study sites, to examine systemic (serum) and local (BAL) antibody responses, and to test the hypotheses that the level of antibodies to the predominant variant is correlated with PCP status.

The IHOP Study serves as the foundation for complementary research studies, led by MU-UCSF Investigators William Worodria, MBChB, MMed, J. Lucian (Luke) Davis, MD, and Adithya Cattamanchi, MD.

Education and Training:
Masters in Public Health (Distance Learning course) 2007 Sept. – ongoing
Makerere University MBChB Degree 1998-2003
Life saving skills training 96 Feb-Sept 1996
Certified Trainer of Trainers in Safe motherhood obstetric care.
Mulago School of Nursing Registered Midwife 1991-1994

MU-UCSF Research Collaboration