Clinical Trials

Cohan D, Gomez E, Greenberg M, Washington S, Charlebois ED. Patient perspectives with abbreviated versus standard pre-test HIV counseling in the prenatal setting:  a randomized-controlled, non-inferiority trial. PLos ONE 2009:4(e5166), (April):1-7. Read Article ...

Charlebois E, Sr. author Havlir D, + others including Kamya M, Achan J, Gasasira A, Rosenthal P, Dorsey G, Ruel T, Wong, J. Short-term HIV disease progression among Ugandan children not yet eligible for ART. (in progress)

Ssewanyana I, Baker CAR, Ruel T, Bousheri S, Kamya M, Dorsey G, Rosenthal PJ, Charlebois E, Havlir D, Cao H. The distribution and immune profile of T cells subsets in HIV infected children from Uganda. (AIDS Research and Human Retroviruses, 2009 Jan;25(1):65-71). Read Article ...

Ruel T, Ssewanyana I, Achan J, Gasasira A, Kamya MR, Kekitiinwa A, Wong J, Cao H, Havlir D, Charlebois E. Dynamics of T-cell activation accompanying CD4 recovery in antiretroviral treated HIV-infected Ugandan children. Clinical Immunology, Volume 131, Issue 3, June 2009, Pages 410-414. Read Article ...

Ruel T, Achan J, Gasasira AF, Charlebois ED, Mebrahtu T, Rosenthal PJ, Dorsey G, Kamya MR, Kekitiinwa A, Wong J, Havlir DV. HIV RNA suppression among HIV-infected Ugandan Children with Measles. JAIDS 2008:48(2), (1 June):225-227). Read Article ...

Kamya MR, Yeka A, Bukirwa H, Lugemwa M, Rwakimari JB, Staedke SG, Talisuna AO, Greenhouse B, Nosten F, Rosenthal PJ, Wabwire-Mangen F, Dorsey G. Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of uncomplicated falciparum malaria: A randomized clinical trial at a high transmission site in Uganda. PLoS Clinical Trials 2007;2(5):e20.
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Njama-Meya D, Clark TD, Nzarubara B, Staedke S, Kamya MR, Dorsey G. Treatment of malaria restricted to laboratory confirmed cases: a prospective cohort study in Ugandan children. Malaria Journal 2007;6:7. Read Article ...

Zongo I, Dorsey G, Rouamba N, Tinto H, Dokomajilar C, Guiguemde RT, Rosenthal PJ, Ouedraogo JB. Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in Burkina Faso: a randomized controlled trial. Lancet 2007;369:491-98. Read Article ...

Dorsey G, Staedke S, Clark TD, Njama-Meya D, , Nzarubara B, Maiteki-Sebuguzi C, Dokomajilar C, Kamya MR, Rosenthal PJ. Combination therapy for the treatment of uncomplicated falciparum malaria: a longitudinal randomized clinical trial in a cohort of Ugandan children. JAMA 2007;297(20):2210-9. Read Article ...

Bukirwa H, Yeka A, Kamya MR, Talisuna A, Banek K, Bakyaiti N, Rwakimari JB, Rosenthal PJ, Wabwire-Mangen F, Dorsey G, Staedke S. Amodiaquine plus artesunate versus artemether-lumefantrine for the treatment of uncomplicated malaria in Tororo, Uganda: a randomized controlled trial. PLoS Clinical Trials 2006;1(1):e7. Read Article ...

Zongo I, Dorsey G, Rouamba N, Dokomajilar C, Lankoande M, Ouedraogo JB, Rosenthal PJ. Amodiaquine, sulfadoxine-pyrimethamine, and combination therapy for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. American Journal of Tropical Medicine and Hygiene 2005;73(5):826-32. Read Article ...

Yeka A, Banek K, Bakyaita N, Staedke SG, Kamya MR, Talisuna A, Kironde F, Nsobya S, Kilian A, Slater M, Reingold A, Rosenthal PJ, Wabwire-Mangen F, Dorsey G. Artemisinin versus non-artemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. PLoS Medicine 2005;2(7):e190. Read Article ...

Bakyaita N, Dorsey G, Yeka A, Banek K, Staedke SG, Kamya MR, Talisuna A, Kironde F, Nsobya S, Langi P, Kilian A, Reingold A, Rosenthal PJ, Wabwire-Mangen F. Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multi-site trial to guide national policy in Uganda. American Journal of Tropical Medicine and Hygiene 2005;72(5):573-80. Read Article ...

Staedke SG, Mpimbaza A, Kamya MR, Nzarubara BK, Dorsey G, Rosenthal PJ. Combination therapies for uncomplicated falciparum malaria in Kampala, Uganda: a randomized clinical trial. Lancet 2004;364(9449):1950-7. Read Article ...

Dorsey G, Gasasira AF, Machekano R, Kamya MR, Staedke SG, Hubbard A. The impact of age, temperature, and parasite density on treatment outcomes from antimalarial clinical trials in Kampala, Uganda. American Journal of Tropical Medicine and Hygiene 2004;71(5):531-6. Read Article ...

Dorsey G, Vlahos J, Kamya MR, Staedke SG, Rosenthal PJ. Prevention of increasing rates of treatment failure by  combining sulfadoxine-pyrimethamine with artesunate or amodiaquine for the sequential treatment of malaria. Journal of Infectious Diseases 2003;188(8):1231-8. Read Article ...

Gasasira AF, Dorsey G, Nzarubara B, Staedke SG, Nassali A, Rosenthal PJ, Kamya MR. Comparative efficacy of aminoquinoline-antifolate combinations for the treatment of uncomplicated falciparum malaria in Kampala, Uganda. American Journal of Tropical Medicine and Hygiene 2003;2(6) 68:127-32. Read Article ...

Dorsey G, Njama D, Kamya MR, Cattamanchi A, Kyabayinze D, Staedke SG, Gasasira A, Rosenthal PJ.  Sulfadoxine/pyrimethamine alone or in combination with amodiaquine or artesunate for treatment of uncomplicated malaria: a longitudinal randomized trial. Lancet 2002;360:2031-38. Read Article ...

Dorsey G, Njama D, Kamya MR, Cattamanchi A, Kyabayinze D, Staedke SG, Gasasira A, Rosenthal PJ. Sulfadoxine/pyrimethamine alone or with amodiaquine or artesunate for treatment of uncomplicated malaria: a longitudinal randomised trial. Lancet 2002 Dec 21-28;360(9350):2031-8. Read Article ...

Staedke S, Kamya MR, Dorsey G, Gasasira A, Ndeezi G, Charlebois ED, Rosenthal PJ. Comparative efficacy of sulfadoxine-pyrimethamine, amodiaquine, and combination therapy for the treatment of uncomplicated falciparum malaria in Kampala, Uganda. Lancet 2001;358:368-74. Read Article ...

Kamya M, Dorsey G, Gasasira A, Ndeezi G, Babirya J, Steadke S, Rosenthal PJ.  The comparative efficacy of chloroquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Kampala, Uganda. Transaction of the Royal Society of Tropical Medicine and Hygiene 2001; 95:1-6. Read Article ...

Dorsey G, Kamya MR, Ndezi G, Babiryi J, Rosenthal PJ.  Predictors of chloroquine treatment failure in children and adults with falciparum malaria in Kampala, Uganda. American Journal of Tropical Medicine and Hygiene 2000;62:686-92. Read Article ...