Molecular Markers

Nsobya SL, Dokomajilar C, Joloba M, Dorsey G, Rosenthal PJ. Resistance-mediating Plasmodium falciparum pfcrt and pfmdr-1 alleles after treatment with artesunate-amodiaquine in Uganda. Antimicrobial Agents and Chemotherapeutics 2007: in press.
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Dokomajilar C, Lankoande ZM, Dorsey G, Zongo I, Ouedraogo JB, Rosenthal PJ. Molecular polymorphisms and resistance to amodiaquine and sulfadoxine-pyrimethamine for the treatment of malaria in Burkina Faso. American Journal of Tropical Medicine and Hygiene 2006;162-165. Read Article ...pdf

Dokomajilar C, Nsobya SL, Greenhouse B, Rosenthal PJ, Dorsey G. Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine from a highly endemic area of Uganda. Antimicrobial Agents and Chemotherapeutics May 2006;1893-1895. Read Article ...pdf


Francis D, Nsobya SL, Talisuna A, Yeka A, Kamya MR, Machekano R, Dokomajilar C, Rosenthal PJ, Dorsey G. Geographic differences in antimalarial drug efficacy explained by differences in endemicity and not molecular markers of drug resistance. Journal of Infectious Diseases 2006;193(7):978-86. Read Article ...pdf


Dorsey G, Dokomajilar C, Kiggundu M, Staedke SG, Kamya MR, Rosenthal PJ. Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda. American Journal of Tropical Medicine and Hygiene 2004;71(6):758-63. Read Article ... pdf


Staedke SG, Sendagire H, Lamola S, Kamya MR, Dorsey G, Rosenthal PJ. Relationship between age, molecular markers, and response to sulfadoxine-pyrimethamine treatment in Kampala, Uganda. Tropical Medicine and International Health 2004;9(5):624-9. Read Article ... pdf


Kyabayinze D, Cattamanchi A, Kamya MR, Rosenthal PJ, Dorsey G. Validation of a simplified method for using molecular markers to predict sulfadoxine-pyrimethamine treatment failure in African children with falciparum malaria. American Journal of Tropical Medicine and Hygiene 2003;69:247-52. Read Article ...pdf


Dorsey G, Kamya MR, Singh AJ, Rosenthal PJ. Polymorphisms in Plasmodium falciparum pfcrt and pfmdr-1 genes and in vivo chloroquine resistance in Kampala, Uganda.  Journal of Infectious Diseases 2001;183:1417-20. Read Article ...pdf